Caryophyllene: Caryophyllene, also known as beta-caryophyllene or β-caryophyllene, gives a spicy, peppery bite to some cannabis strains. Caryophyllene is also found in cloves, rosemary, oregano, and black pepper. Caryophyllene is the only known terpene found in cannabis that can bind to the CB2 receptor in the endocannabinoid system. Caryophyllene is sometimes also classed as an atypical cannabinoid. Research into caryophyllene shows that it has potential in easing symptoms in diverse conditions such as colitis, diabetes, cerebral ischemia, anxiety and depression, liver fibrosis and Alzheimer-like diseases. Future research suggests that caryophyllene’s activity at the CB2 receptor could be harnessed to help treat conditions that are accompanied by inflammatory symptoms.